LCS101 Ingredients

A table of the 14 botanical ingredients  of the formula LCS101 with scientific references for their effect:
Botanical NameAnti-Cancer (in vitro, in vivo)Immune SystemChemo Side Effects, Protection
Astragalus membranaceus
Huang Qi
Glioma[1]
Myeloid tumors [2]
T cells [3-5]; Macrophages [2, 6-8]
B cells [5, 6, 9]
LAK cells [10, 11]
Anti-inflammatory [12, 13] General [6, 9, 14]
Immune system [5, 6, 15, 16] Heart [17-19]
Liver [20]
Renal [21]
Anti-mutagenic [22]
Atractylodes macrocephala
Bai Zhu
Leukemia & lymphoma [23]Anti-allergic [24] 
Citrus reticulata
Chen Pi
Colon [25]
Gastric [26]
Anti-inflammatory [27-29]Cell protection [30]
Glehnia littoralis
Bei Sha Shen
 Anti-inflammatory [32, 33] 
Ligustrum lucidum
Nu Zhen Zi
Glioma [34]T cells [4]
Anti-inflammatory [35] Macrophages [7]
Anti-mutagenic [22]
Lycium chinense
Gou Qi Zi
  Liver [36, 37]
Bone marrow [38]
Milletia reticulata
Ji Xue Teng
 Anti-inflammatory [39] 
Oldenlandia diffusa
Bai Hua She She Cao
Melanoma [40]
Renal cell carcinoma [41]
T cells [42]
Anti-inflammatory [43]
Macrophages [41, 44]
General [9]
Anti-mutagenic [22, 45, 46]
Ophiopogon japonicus
Mai Men Dong
 Anti-inflammatory [48]Adaptogens: Strength, Stamina [49]
Paeonia lactiflora
Bai Shao
Bladder cancer in vivo [51]  
Poria cocos
Fu Ling
 Anti-inflammatory [52, 53]
Immuno-stimulatory [54]
 
Prunella vulgaris
Xia Ku Cao
NSCLC [55, 56]
Melanoma
(lung metastasis) [57]
Anti-inflammatory [58, 59]
Macrophages [60]
 
Scutellaria barbata
Ban Zhi Lian
Breast cancer [61-63]Prostate cancer prevention [64]
Renal cell carcinoma [41]
Macrophages [41]Anti-mutagenic [22, 45, 46]

References

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25. Kang SA, Park HJ, Kim MJ, Lee SY, Han SW, Leem KH: Citri Reticulatae Viride Pericarpium extract induced apoptosis in SNU-C4, human colon cancer cells. J Ethnopharmacol 2005, 97(2):231-235.
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40. Gupta S, Zhang D, Yi J, Shao J: Anticancer activities of Oldenlandia diffusa. J Herb Pharmacother 2004, 4(1):21-33.
41. Wong BY, Lau BH, Jia TY, Wan CP: Oldenlandia diffusa and Scutellaria barbata augment macrophage oxidative burst and inhibit tumor growth. Cancer Biother Radiopharm 1996, 11(1):51-56.
42. Shan BE, Yoshida Y, Sugiura T, Yamashita U: Stimulating activity of Chinese medicinal herbs on human lymphocytes in vitro. Int J Immunopharmacol 1999, 21(3):149-159.
43. Kim SJ, Chung WS, Kim SS, Ko SG, Um JY: Antiinflammatory effect of Oldenlandia diffusa and its constituent, hentriacontane, through suppression of caspase-1 activation in mouse peritoneal macrophages. Phytother Res 2011, 25(10):1537-1546.
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45. Wong BY, Lau BH, Teel RW: Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism of benzo[a]pyrene 7,8-dihydrodiol and benzo[a]pyrene 7,8-dihydrodiol-9,10-epoxide. Cancer Lett 1992, 62(2):123-131.
46. Wong BY, Lau BH, Yamasaki T, Teel RW: Inhibition of dexamethasone-induced cytochrome P4-mediated mutagenicity and metabolism of aflatoxin B1 by Chinese medicinal herbs. Eur J Cancer Prev 1993, 2(4):351-356.
47. Song YH, Jeong SJ, Kwon HY, Kim B, Kim SH, Yoo DY: Ursolic acid from Oldenlandia diffusa induces apoptosis via activation of caspases and phosphorylation of glycogen synthase kinase 3 beta in SK-OV-3 ovarian cancer cells. Biol Pharm Bull, 35(7):1022-1028.
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51. Ou TT, Wu CH, Hsu JD, Chyau CC, Lee HJ, Wang CJ: Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo. J Ethnopharmacol 2011, 135(1):162-172.
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54. Yu SJ, Tseng J: Fu-Ling, a Chinese herbal drug, modulates cytokine secretion by human peripheral blood monocytes. Int J Immunopharmacol 1996, 18(1):37-44.
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57. Choi JH, Han EH, Hwang YP, Choi JM, Choi CY, Chung YC, Seo JK, Jeong HG: Suppression of PMA-induced tumor cell invasion and metastasis by aqueous extract isolated from Prunella vulgaris via the inhibition of NF-kappaB-dependent MMP-9 expression. Food Chem Toxicol 2010, 48(2):564-571.
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64. Wong BY, Nguyen DL, Lin T, Wong HH, Cavalcante A, Greenberg NM, Hausted RP, Zheng J: Chinese medicinal herb Scutellaria barbata modulates apoptosis and cell survival in murine and human prostate cancer cells and tumor development in TRAMP mice. Eur J Cancer Prev 2009, 18(4):331-341.
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